Dr. Ehrlich's Magic Bullet

Synopsis: Dr. Paul Ehrlich was the German physician who developed the first synthetic antimicrobial drug, 606 or Salvarsan. The film describes how Ehrlich first became interested in the properties of the then-new synthetic dyes and had an intuition that they could be useful in the diagnosis of bacterial diseases. After this work met with success, Ehrlich proposed that synthetic compounds could be made to selectively target and destroy disease causing microorganisms. He called such a drug a "magic bullet". The film describes how in 1908, after 606 attempts, he succeeded.
Genre: Biography, Drama
Director(s): William Dieterle
Production: Unknown
 
IMDB:
7.5
APPROVED
Year:
1940
103 min
160 Views


'Next. '

What you have

is a contagious disease.

An infection

just like any other.

I have seen cases

where it was transmitted

By an inanimate object.

You mustn't be disheartened.

There are many

as badly off as you.

- Many.

- Will I get well?

You must come here

twice weekly for sweat baths

Observation

and medical supplies.

The treatment consists largely

in rubbing yourself

With this ointment.

Tell me, doctor.

Will I get well?

Rub a different part of skin

every night of the week

So that no part of the skin

is rubbed more than once weekly.

There is this girl in Munich

With whom I'm in love,

who loves me.

We had planned to be married

as soon as I graduate.

Tell me, doctor.

Tell me the truth.

Can we ever get married now?

I'm afraid marriage

is out of question, Hans.

You may dress now.

Does anybody ever get cured?

Of course, there've been

many cured, many.

Come in.

Ehrlich, you haven't

returned yesterday's reports.

I need them.

Oh, I'm sorry.

Oh, they should be over there.

- Next.

- Next?

It's almost one o'clock.

The nurses are complaining.

The clinic closes at 12.

I can't be short with them,

poor devils. I simply can't.

- You're hopeless.

- Did you find them?

Doctor, will you

sign this order?

Yes, yes.

Dr. Ehrlich, have you

a moment for me?

- What is it, Merk?

- Doctor, the order.

Sweat baths, they take

away my strength.

I'm too weak

to work after taking them.

I'm afraid I'll lose my job.

- A teamster, aren't you?

- Yes.

I think we can dispense with

the sweat baths in your case.

- Oh, thank you, sir.

- Come back next week.

Thank you, doctor.

Doctor, will you

please sign...

Oh, yes, of course.

Ehrlich, you shouldn't have

changed the patient's treatment.

Why not?

Our superior, Geheimrat Hartmann

has ordered

Sweat baths in such cases.

You know as well as I do,

they're of no value.

That's beside the point.

Why should he lose

his job because of us?

Never mind,

Sweat baths was the order.

Merk is my patient.

I don't see in what way

this affects you.

A hospital is an organization,

an organization must have rules

And rules have to be

obeyed by everyone.

He's much better off now.

And the world's a better place

to live in too.

'Cause there isn't any chance of

his infecting someone else now.

Please, Paul, drink your coffee.

No use saying things

like that. No use at all.

Neither are the treatments

I prescribe of any use.

You do everything in your power.

Everything in my power

amounts to nothing.

I told him

that others have got well...

But he looked into me

and saw the lie.

He read the lie in me.

Hedi... I'm going to resign.

Quit the hospital.

I can't endure it any longer.

Quit the hospital?

To do what, Paul?

Try and find out something.

We know so little

in medicine. So very little.

We're groping in the dark

Bumping into things, the nature

of which we don't know.

If you are unhappy,

Paul, very unhappy...

Then, of course,

you must leave the hospital.

We should manage somehow.

Drink your coffee, Paul.

Hello, mama.

Papa.

How was school today?

Did you learn your lesson?

- Yes, Papa, I did...

- No, she didn't.

- She didn't know the answer.

- Who's telling the truth?

- 'I did. '

- 'She's not. '

Take me piggy back, papa.

Alright, up you go.

Of course, you did,

darling. I know.

Faster, papa, faster.

Faster, daddy, faster, faster.

Thank you, papa. That was fun.

I'm so hungry.

Drink your milk slowly, dear,

like a good girl.

More, mama, more.

Oh, the amount

of milk they drink.

Please, may I have

some more too?

Um, three quarts

a day between them.

How much is a quart

of milk, Hedi?

Twenty pfennig

and the price is going up.

Hm.

If one quart costs 20 pfennig,

what would three quarts cost?

- Seven pfennig.

- Oh, no.

- Sixty pfennig, isn't it, Papa?

- Yes.

Oh, almost five o'clock. I must

be getting back to the hospital.

- Goodbye.

- Bye.

Bye, Papa.

Don't spill that milk

on your dress, dear.

How long will it be, Paul,

before you quit the hospital?

Oh, I'm not

quitting the hospital.

But you just said...

Well, I was just

letting off steam.

I've changed my mind.

- Oh, Paul, your hat.

- Mm, oh.

Thank you.

Good evening,

Herr Sensenbrenner.

Are you intending to use

my laboratory again?

Yes.

The other day,

after you were through

I found all my chemicals

and dyes in a litter.

- Nothing was in its place.

- Oh, I'm sorry.

Other people don't come in here

messing things up like you.

Now, Sensenbrenner,

is that the way for one

Fellow scientist

to talk to another?

- I'm not a scientist.

- Aw.

I know my place if other

people don't know theirs.

And don't call me Sensenbrenner.

I'm Herr Sensenbrenner to you.

Well, Herr Sensenbrenner,

I beg of you

Permit me the use

of your laboratory.

Will you clean

up after you're through?

- Gladly.

- Very well.

Good evening.

I'm Dr. Behring

of the Koch Institute.

Are you Herr Sensenbrenner?

Herr Sensenbrenner

just went home.

Oh, he was supposed to leave

A throat culture

of a diphtheria case for me.

Oh.

But it should

be in the incubator.

Koch Institute. Here we are.

Yeah, thank you very much.

Goodnight.

Are you connected

with the Koch Institute?

That's right.

Well, I envy you working

under one like Robert Koch.

It must be an inspiration.

He's such a great man.

- Indeed he is.

- Are you on diphtheria?

Just beginning.

Have you verified

the work done

At the Pasteur Institute?

Louis' experiments?

That's where

I'm about at the moment.

Well, if proven,

his contention will change

Our whole perception

of bacteriology.

True, so if you

realize that thing.

What department

are you in doctor?

Dermatology.

It's extraordinary

that you should be so...

Well informed

on the subjects

So far removed

from your own field.

Are you interested

in microscopic findings?

Well, I've been

experimenting with dyes.

The new anilines.

Trying various combinations

and their effect on cells.

If you'd care

to see some slides?

I'll be delighted.

- Extraordinary!

- Hm?

'The nuclei of the

white blood cells are deep blue. '

This is by far

the clearest picture

Of human blood

I've ever seen.

It seems the chemical

make-up of the nuclei

Has a special

affinity for this dye.

What do you mean affinity?

The attraction, certain atoms

possess for certain other atoms

Causes them to unite

and form compounds.

Most extraordinary.

A few minutes ago

I injected a living worm

With a dye I call

methylene blue.

It has an affinity

for the nerves of the worm.

The same phenomenon.

The whole nervous system blue.

It is blue, upon injection

into the blood stream

The dye circulated

to the worm's body.

It combined with the nerves.

The nerves and nothing else.

Wonderful!

It all depends upon discovering

the special dye which has

An affinity to the substance,

one which is to stain.

Specific staining.

Great heavens!

What about a microbe?

Do you think it'd be possible...

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John Huston

John Marcellus Huston (; August 5, 1906 – August 28, 1987) was an Irish-American film director, screenwriter and actor. Huston was a citizen of the United States by birth but renounced U.S. citizenship to become an Irish citizen and resident. He returned to reside in the United States where he died. He wrote the screenplays for most of the 37 feature films he directed, many of which are today considered classics: The Maltese Falcon (1941), The Treasure of the Sierra Madre (1948), The Asphalt Jungle (1950), The African Queen (1951), The Misfits (1961), Fat City (1972) and The Man Who Would Be King (1975). During his 46-year career, Huston received 15 Oscar nominations, won twice, and directed both his father, Walter Huston, and daughter, Anjelica Huston, to Oscar wins in different films. Huston was known to direct with the vision of an artist, having studied and worked as a fine art painter in Paris in his early years. He continued to explore the visual aspects of his films throughout his career, sketching each scene on paper beforehand, then carefully framing his characters during the shooting. While most directors rely on post-production editing to shape their final work, Huston instead created his films while they were being shot, making them both more economical and cerebral, with little editing needed. Most of Huston's films were adaptations of important novels, often depicting a "heroic quest," as in Moby Dick, or The Red Badge of Courage. In many films, different groups of people, while struggling toward a common goal, would become doomed, forming "destructive alliances," giving the films a dramatic and visual tension. Many of his films involved themes such as religion, meaning, truth, freedom, psychology, colonialism and war. Huston has been referred to as "a titan", "a rebel", and a "renaissance man" in the Hollywood film industry. Author Ian Freer describes him as "cinema's Ernest Hemingway"—a filmmaker who was "never afraid to tackle tough issues head on." more…

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