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Mary-Louise Parker (born August 2, 1964) is an American actress and writer. After making her stage debut as Rita in a Broadway production of Craig Lucas's Prelude to a Kiss in 1990 (for which she received a Tony Award nomination), Parker came to prominence for film roles in Grand Canyon (1991), Fried Green Tomatoes (1991), The Client (1994), Bullets over Broadway (1994), Boys on the Side (1995), The Portrait of a Lady (1996), and The Maker (1997). Among stage and independent film appearances thereafter, Parker received the Tony Award for Best Actress in a Play for her portrayal of Catherine Llewellyn in David Auburn's Proof in 2001, among other accolades. Between 2001 and 2006, she recurred as Amy Gardner on the NBC television series The West Wing, for which she was nominated for the Primetime Emmy Award for Outstanding Supporting Actress in a Drama Series in 2002. She received both the Golden Globe and Primetime Emmy Awards for her portrayal of Harper Pitt on the acclaimed HBO television miniseries Angels in America in 2003.

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