Extraordinary Measures Page #4

Most of us here are scientists.

We need to see the science.

Bob, make us believe.

Love to, George.

(INAUDIBLE)

...the phosphotransferase and

the 2nd uncovering enzyme...

STONEHILL:
At this point,

the challenge is to scale up this process

to produce kilogram

quantities of HPGAA.

And the question is

whether or not it's cost-effective

to contract this work out or to build

our own manufacturing facility.

Either way, we're gonna

eventually need

an investment on

the order of $10 million.

It's a lot of information

in a short period of time.

Does anybody

have any questions?

This is astonishing.

STONEHILL:
Well, thank you, George.

This man is light years

ahead of the field.

(CHUCKLES)

Okay.

Well, why don't you have your

money guys get together with John

and work out

the business...

Sounds great.

Of course, we'll need you to explain

some of the mundane stuff, Bob,

the nuts and bolts.

Nuts and bolts? What...

RENZLER:
Yeah.

You're a brilliant

theoretician,

but you've never actually

brought a new drug

to market

before, right?

No, I've never brought a drug to market.

I haven't.

(CLEARS THROAT)

I mean, for example,

how are you getting

the phosphotransferase?

I'm purifying it out of

a lactating bovine udder.

I see. And where are

you getting the udders?

From the stockyards.

Pretty straightforward stuff.

Not really.

You can't inject cow

protein into people.

I know that.

The bovine version

of the enzyme

is for lab work,

for proof of concept.

I'll make a copy of the human enzyme

for actual drug trials.

What about uncovering enzyme?

What about it?

How exactly do you plan

on making an exact replica?

I'm making it in T-293,

out of human kidney cells.

Oh, my goodness. No.

"Oh, my goodness. No?"

No. The FDA will

never allow that.

Hey, Bob, just...

Wait a second.

For Christ's sake, we will change

the cell line before clinical trials.

You've gotta have

that process locked down

long, long before

you think about...

Bob, why don't we just

take a coffee break...

Why are you

talking to me this way?

I don't want any goddamn coffee.

Bob, can you just tell us

how you're planning to make

the 3 enzymes under

FDA-approved GMP in...

I'm not here to cross every "t"

and dot every "i", George.

And I'm not here to

be poked and prodded

like a 1st-year med student.

This is ridiculous.

Bob.

This is bullshit.

RENZLER:

Bob.

Bob, if you can't

answer a question,

you say you're

working out the details.

You don't storm out

on these guys

like some sort of

spoiled child, okay?

Now, we're gonna

go back in there.

No, I'm not going

back in there.

We're going back in there.

This is business, Bob. It's not personal.

That was personal.

Stonehill goes and completely

sabotages the meeting.

Thank you.

I mean, he completely blew my plan,

right out of the gate.

Okay, I get that

he's a loose cannon,

but do you still

believe in his science?

Honey, if I don't raise

$10 million in capital,

his science doesn't

matter. At all.

What's going on

with his arm?

Hey, buddy, you okay?

You all right?

I can't throw them anymore.

When did this happen?

I don't know.

You should help him, Daddy.

That's a good idea.

Okay, here we go. You ready?

Into the water.

That was a good shot.

We can do better than that.

Try again.

Let's make, like, a little pellet.

Here, ducky, ducky.

(ALL LAUGHING)

Let's do it again.

Ready? 1, 2, 3.

Give me another piece, John.

(CHUCKLING)

Oh.

I can just throw them.

And you do all the laughing,

and I'll do all the throwing.

JOHN:

That's good, the ducky shared.

Did you see that?

PATRICK:
Yeah.

John?

We're out of time.

I know.

He doesn't have the strength to

throw a piece of bread to a duck.

It scares the hell out of me.

Me, too.

John, what are you doing?

I'm offering Renzler

a deal he can't turn down.

Excuse me.

Morning. Dr. Renzler?

Dr. Renzler?

Sir, good morning.

John Crowley.

Crowley?

Yes, sir.

What are you doing here?

Good morning.

Good morning.

I understand from

your secretary that

you're going to be

leaving for France

for a month.

That's right.

I have a proposal for you,

and I was hopeful

that you could

take a look at it.

We're running

late for a flight.

I appreciate that. It'll only take a second,

just to have a quick read.

Fine. I'll read it in the car.

It might interest you.

Good, thank you.

Does Stonehill know about this?

Of course.

And he's okay with these terms?

All I need is your signature.

Hello?

I just need some place

Where I can lay my head

Bob.

Bob.

(KNOCKING ON WINDOW)

JOHN:

Bob!

Over here.

Bob.

Ow!

Bob!

(THE WEIGHT PLAYING)

Hi. Bob.

What'd you do to yourself?

I got the investment from Renzler.

You what?

Listen, I want you to

think about something

before you read that.

What the hell is this?

Under the circumstances, this is

the best deal that we could ever get.

This isn't a deal.

This is the terms of our surrender, for...

Renzler comes in for

a couple million now,

and you give him the option

of jumping in as a full partner later?

Well, after sabotaging our meeting,

I had to do something dramatic.

And you promise him we'll be

in clinical trials in a year?

We can do this, Bob.

All right?

We work harder, we push ourselves,

we work around the clock.

I already work around the clock!

Why don't you just give 'em

my balls in a jelly jar?

There's no other way I could get

them to come back to the table.

Who needs the bastards anyway!

Without Renzler,

there's no reason for us

to even think about

other venture groups.

Fine! Then I won't think about

other venture groups!

Great!

Spend the rest of

your life dreaming up

great ideas that

don't get funded.

Draw brilliant diagrams on the wall

that cure diseases in theory,

but never help a single

human being in reality.

What'd you do?

Let me see it.

It's just barely...

Let me see.

Put pressure on it.

Got your blood

all over this thing.

Want me to add a drop of mine,

make it official?

Or would a

signature suffice?

Bob?

(THE WEIGHT CONTINUES PLAYING)

I picked up my bag

I went lookin' for

a place to hide

When I saw Carmen and

the Devil walkin' side by side

I said, "Hey, Carmen, come on,

let's go downtown."

She said, "I gotta go,

but my friend can stick around"

Take a load off, Fanny

Take a load for free

I'm not paying a dollar more

than 22,000 a unit, okay?

I'm not doing it.

Hi, Bob.

These guys

make me feel old.

Scientists get all sensible and

careful when they get old.

Young ones like risk,

not afraid of new ideas,

and you can pay 'em less.

We all believe in Bob Stonehill's

bold vision, otherwise

you wouldn't be here.

But to reach clinical

trials inside of a year,

I'm gonna have to ask you

to commit to a brutal schedule.

Ladies and gentlemen,

reset your watches to Priozyme Time.

How long?

Well, if you can get it any quicker,

that'd be good.

NILES:

I'll try.

MAN:

Come on.

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