Extraordinary Measures Page #7

Synopsis: A Portland couple have two children with Pompe disease, a genetic anomaly that kills most before a child's tenth birthday. The husband, John, an advertising executive, contacts Robert Stonehill, a researcher in Nebraska who has done innovative research for an enzyme treatment. He has little money to fund his laboratory, and a thorny personality that drives away colleagues and funders. John and his wife Aileen raise money to help Stonehill's research and the required clinical trials. John takes on the task full time, working with venture capitalists and then rival teams of researchers. Time is running short, Stonehill's angry outburst hinder the company's faith in him, and the profit motive may upend John's hopes. The researchers race against time for the children who have the disease.
Genre: Drama
Director(s): Tom Vaughan
Production: CBS Films
  1 win.
 
IMDB:
6.5
Metacritic:
45
Rotten Tomatoes:
28%
PG
Year:
2010
106 min
$11,854,694
Website
991 Views


green and magenta,

and known only by

those color codes

so no researcher will know

which one he's testing.

Only after we pick a winner,

the secret identity will be revealed.

GIRL:

Come on, Megan!

GIRL:

But I want to!

JOHN:

Just roll your wrist.

I can't.

It's okay. It's all right.

Let's try another one.

Okay. Let's try again. Ready?

Ready?

(KIDS CHEERING)

Big winner!

Yay!

Here you go, look at that.

You got a penguin.

(ROCK MUSIC PLAYING)

JOHN:

Hey, Bob. Bob.

How you doin'?

I brought you some ribs.

Not as good as the ones

from The Corner Saloon,

but if you're hungry...

(MUSIC STOPS)

What do you want?

The results.

"Mother of All Experiments."

Well,

which enzyme did they choose?

The leadership team spent

the whole afternoon arguing.

are ahead of the others,

but it's too close to call.

Tomorrow, we spend

the day hashing it out

to decide which one to choose.

Bob. I'm asking you to read this.

I value your opinion more than

anyone else in the world.

Well, maybe you should have valued

my opinion a little sooner,

instead of playing hatchet man

for the bean counters.

Get the hell out of my lab.

It's in your interest

to know about this, Bob.

Get out.

Wouldn't it benefit you...

Get out.

The green enzyme's the best.

Show 'em my analysis, they'll understand.

Hey, wait up, Bob.

Is the green enzyme yours?

I recognize patterns

in the results.

I'd know my baby

a mile away.

So the green one is yours?

No.

No, it's not.

My theory is still the best,

but it's not ready for manufacture.

Theirs is crude and uninspired,

but it's ready.

Bob, I don't even know

the words to say thank you.

Don't bother.

I didn't do it for you.

JOHN JR.:

Yes, it is!

Oh, my gosh.

Do you see the kite up there?

Yeah.

That's so cool!

JOHN:

Annie, careful!

Building a bastion.

AILEEN:

Right there. Yeah.

(PHONE RINGING)

Okay!

Dad, like...

Ready?

Dad, you promised

no more phone calls.

I know. I know I did, but...

What's in there?

We can take turns burying

the phone when I get back.

Okay! I'll start digging a hole.

You hold that for a sec.

John Crowley.

John, it's Kent Weber.

Kent, hey. Did you get my suggested

protocol for the clinical trials?

Yeah.

You made some pretty

optimistic assumptions

about where our

enzyme supply will be.

I see.

Well, what do you think

that a more realistic...

John, I'll give to you straight.

The clinical trial

will be for infants only.

(EXCLAIMS)

Infants need so

much less enzyme,

and, as you know,

our initial supply will be so limited.

And the drug has much higher

odds of being effective

with infants than

with older children.

We have to consult Erich on this.

We have to consult Erich.

I already did. He confirmed

the decision. Infants only.

I understand your

personal reasons for...

(SIGHS)

These decisions have to be

made objectively, rationally.

I'm sorry. I...

I really am.

(ENGINE STARTING)

(ELECTRONIC WHIRRING)

GUARD:

Hold it, pal.

Mr. Crowley, what are you

doin' in here?

I was just...

You're not authorized.

No... I can

explain everything.

What's the matter, Chuck?

Is there a problem?

Yeah, there's a problem. I got

Mr. Crowley in here without clearance.

That's my fault, now.

I got busy in the lab,

I sent Jersey boy here

to get me a couple

jugs of enzyme.

Sorry.

Thanks, Chuck.

Thanks for saving my ass.

It's really big of you,

especially after what

went down between us.

You mean your ruthless,

cold-hearted betrayal?

Yeah, well, when I thought

about it from your point of view...

Sh*t, if it was my

kids dying, I wouldn't

have hesitated to

crush you like a bug.

Do you remember

when we first met,

and you told me that

I should stop chasing miracles

and should go home

and enjoy my kids,

while they're still here?

Yeah. I made the wrong choice.

Jersey, you know

what a sibling study is?

No.

It's a drug trial with just 2 patients

with the same genetic inheritance.

Siblings, with the same disease.

Megs and Patrick.

Well, would Zymagen

go for something like this?

There's real research value in it.

And with just two patients,

it wouldn't take much enzyme.

But Webber would

have to sign off on it.

Well, let's not tell him till

we've got our ducks in a row.

I could draw up a protocol

and see if I can find

a hospital willing

to administer it.

Bob.

Well, don't get your hopes up, kid.

It's a Hail Mary.

(READING)

Ducks in a row.

"Stonehill, careful review,

protocol, Sibling Trial, 146,

"are pleased to inform you

Megan Crowley and Patrick

"have been accepted

into the trial!"

I just got it.

Quack, quack, quack.

Have you talked to him yet?

No. I did the science.

You make the sale.

Thank you.

Good luck.

Right.

Does he have about 5?

RECEPTIONIST:
He does, yeah.

Thanks.

No problem, Mr. Crowley.

Hey, Kent? Knock-knock.

Got a minute?

Kent?

Do you have any idea what you've done?

Excuse me?

We got a call this morning from

Portland Rose Hospital,

about sending them

enzyme for your kids?

Right. Yeah, I know.

That's what I'm here to talk to you about.

You and Stonehill set this up behind

my back. Now you come to me.

It's all tentative.

You want this company

to sponsor a drug study,

for 2 children whose father

is an executive of this company?

Have you never heard the term

"conflict of interest?"

It has nothing to do with a...

Do you know what the FDA

would do if they found out?

There is strong scientific justification

for this study.

There is great research value.

I'm a doctor, John.

I know the research value!

But you guys just can't go off

half-cocked without consulting us!

And I'm sure that if we just go

and talk to Erich, we can...

Erich already knows.

He's furious about

being blindsided.

I didn't try to

blindside anyone.

This is the reason why

we have a reporting structure,

why we have established procedure,

why there is protocol.

You heartless,

bloodless machine.

You just have to fight me every step

of the way! Don't you?

You just hated it

when I brought

the kids with Pompe

to the doorstep!

You weren't thinking

about those kids

when you put your

children into that program

and jeopardized

a decade's worth of

research investment

made by this company!

This is not about

a return on an investment!

It's about kids,

kids with names, dreams,

families that love them.

You've jeopardized

your chances

of ever getting

your kids treated.

(SLAMMING)

(SHOUTING)

I'm not arguing

science with you!

On every level!

On every level, you've stood...

(TAPPING ON DOOR)

I was just drafting a letter of

apology for senior management,

but I guess we're

past that point.

I just spoke to Erich, and we are

terminating your employment.

Okay, I'll pack

up my stuff.

Just one thing, John.

I may well be a tight-ass

pencil-pushing company man,

but I resent being

called heartless.

Look...

Just let me finish.

The reason we're terminating

your employment,

is to eliminate the

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Robert Nelson Jacobs

Robert Nelson Jacobs (born 1954) is an American screenwriter. In 2000, he received an Academy Award nomination for best adapted screenplay for Chocolat. In 2014, Jacobs was elected president of the Writers Guild Foundation, a non-profit organization devoted to promoting and preserving the craft of writing for the screen. more…

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