Extraordinary Measures Page #6

It's an entrepreneurial

model. It works.

I'm all for competition,

but surely there must be some channel

for allowing sharing

scientific insights

that can help develop

all 4 enzymes.

John, in the interest of saving us time,

let me be blunt.

Most of the scientists

here don't like the idea

of having a non-scientist

as senior VP of the Pompe program.

Especially one whose objectivity

might be clouded by having children

with the disease.

I'm telling you this in your own

best interests.

Erich wanted to buy

Stonehill's ideas,

and he couldn't do

that without also

swallowing you as

part of the pill.

My advice to you, John,

is to keep your head down.

Thank you for that wisdom.

You're very welcome.

SCIENTIST:
All of your lab notebooks must

be submitted to the review committee!

STONEHILL:

This is my lab now! Get out!

I'm just trying to

explain the protocol!

STONEHILL:

You're wasting my time.

Dr. Stonehill...

Shoo!

Fine.

Shoo.

What do you want?

I just dropped by

to say that I think

that we might be

missing an opportunity

to open a dialogue with

the other 3 core teams.

The other core teams?

Core teams.

Core bullshit.

I'll come back another time.

DR. WALDMAN:
The decline in muscle

strength is very troubling, of course,

but it's really,

in both kids,

the organ enlargement, the liver,

and especially the heart,

that's the real

threat to their lives.

We'll continue to monitor

the rate of cardiac enlargement.

We'll keep tabs on

their other organs...

How long?

I don't like to predict.

JOHN:
Please.

Dr. Waldman,

we won't hold you to it.

We just need to

know something.

John.

How much more time do we have?

How long?

Well,

if there's another respiratory crisis,

all bets are off,

but otherwise,

Megan, maybe a year.

Patrick, less.

Thank you.

(PHONE RINGING)

WENDY:
Marcus.

Hmm?

Get the phone.

What?

The phone.

Who is it?

MARCUS:

Hello?

Hi. Is that Marcus?

Yeah, yeah.

What time is it?

Yeah, I'm sorry. It's late.

It's John Crowley.

John, what you doin'?

You okay?

(SIGHS)

Hey, look,

I gotta ask you a favor.

Morning, Gavin.

Morning, sir.

Is my 11:
00 with

Henessey confirmed?

Yes, and there's the breakfast

meeting down in the cafeteria.

Breakfast meeting?

There was an e-mail that

came in over the weekend.

Everyone on the Pompe

project was invited.

Who called the meeting?

Mr. Crowley, I believe, sir.

What?

AILEEN:
Um, something

that people ask me all the time

is how we have 2 kids with Pompe.

By the time we realized

that Megan had Pompe,

I was already pregnant

with Patrick.

I mean, I can't tell you

how many doctors we saw,

and the message

was always the same,

that there is no drug

to treat Pompe.

But thanks to you, all of you,

that message is changing.

What you've given us,

and a lot of other families, is hope.

So, thank you.

Good job, Aileen.

Now I'd like to

welcome the Temple family,

who've come all the way from Georgia

to be with us here today.

Thanks, John.

Hi.

I'm Marcus.

This is my wife, Wendy.

Our daughter Lauren,

our oldest daughter,

Lauren wanted to come today

and say hi to all you guys.

She's a little weak,

but she wanted us to show

you guys her picture

and to send you her love.

And this is our daughter, Megan.

The most beautiful

girls are named Megan.

Megan is 4 months old,

and you can't see it yet,

but she has Pompe, too.

I...

I can't tell you what it means to us

to have all of you working on

a medicine for our children.

Thank you.

Thanks so much.

Hey, Kent.

John.

JOHN:

So what did you think of the event?

In medical research, John,

objectivity is key.

If researchers get all emotional,

all desperate to help suffering patients,

they'll cut corners.

It's counterproductive.

Counterproductive is having

working together

on the same disease,

but not talking to each other.

Most of these guys have never even

seen a kid with Pompe before.

I don't see how

that's relevant.

Did you see Erich? That's the kind

of motivation that we need.

I'm gonna ask him

to get the core team

to stop competing,

start working together.

Create a leadership team.

Well, if you hope to sell

this leadership team idea,

there's only one

way to convince Erich.

And what's that?

Keep your guy,

Stonehill, off the team.

In his short tenure here,

he's managed to alienate

a remarkable number

of colleagues.

You can't put him on a team that's

supposed to build cooperation.

So, decide how badly

you want your leadership team,

then do what you have to do.

(ROCK MUSIC PLAYING)

That's it.

Dr. Stonehill, please.

Turn it down. Yes.

Yes, the music.

(VOLUME INCREASES)

I said down!

This guy's impossible.

I like that song.

JOHN:

Hey.

What's up, John?

Everything all right at home?

Yeah.

Have you heard that Erich Loring

has agreed to put together

a leadership team?

Yeah, I heard some rumor about it.

What bullshit.

Now I'm gonna have to spend

a couple of hours a week

jawin' with Zymagen guys?

No.

No. No, you won't, 'cause

I'm not putting you on the team.

What'd you say?

I really wanted to.

You're not putting me on the team?

Is that what you said?

What are you,

some varsity track coach?

They didn't buy our company

'cause they like your

Ivy League charm, Jersey.

It's me they wanted.

You can't bench me.

It's against the laws of nature.

You're still gonna be able to

prove that your theory is right.

Yeah, but other

scientists are gonna

evaluate my results,

right? Not me.

Everyone here

reveres your science.

This is about

interpersonal issues.

Who put you up to this?

The decision was mine.

It's for the overall

good of the program.

"For the overall

good of the program."

Wow, John, you really got

the corporate lingo down good.

What's next, "Acceptable loss?"

JOHN JR.:

No.

JOHN:
Does anybody really

know how to do this?

Except for us.

But wait, who's going?

MEGAN:

It's John's turn still.

(KIDS EXCLAIMING)

Nice one.

(PHONE RINGING)

Okay. I'll get it.

Nice one, Megs.

Hello? Marcus, hi.

Oh, my God.

PATRICK:

Aw, man. I almost got 'em down.

You guys sit tight, okay?

Here, John, grab him.

If there is anything we can do,

anything at all,

will you call?

Okay. We love

you guys so much.

Okay, bye-bye.

Aileen.

That was Marcus Temple.

Lauren...

She...

He said she went in her sleep,

that it was peaceful.

JOHN JR.:

How old is she?

How old was Lauren?

Lauren was 9 years old.

Come here.

JOHN:
That way, we can be certain that

we're developing the correct one.

Forget certainty,

and let's try and figure out

which enzyme has

the better odds.

If we develop

only one enzyme,

what would happen

if we guessed the wrong one?

Mr. Crowley, I've asked Kent

to set up a testing protocol

to help us guess right.

We'll do an exhaustive

range of tests.

I'm calling it

"The Mother of All Experiments."

(ALL CHUCKLING)

The 4 enzymes

will be color-coded,

yellow, blue,

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