Decoding Annie Parker Page #4
- Pardon me?
They eat very little red meat,
and they have a much lower rate
of breast cancer
Is that so?
Yeah.
- So did your family go out...
One was over ten years.
It's fairly conclusive.
Anyway, I'm gonna get going.
- So...
- We can't know anything.
There's so many
possible factors.
It could be diet.
It could be toxins in the home.
One of a thousand viruses
known or unknown.
They know the groups that
have the highest incidents.
They don't know the elements
common to those groups.
We don't know
what happened to your family.
We may never know.
My mom used to wrap
hot dogs in bacon,
and they deep-fried them.
- What's this?
- It's dinner.
Where's the rest of it?
That's it.
It's a salad.
It's got tomatoes in it.
I hate tomatoes.
You can pick them out.
Is everything okay?
Yeah. Yeah.
You know what?
Um, I'm gonna go
get us some burgers.
- You want one?
- Yeah!
But no tomatoes
and no oniony things.
No tomatoes
and no oniony things.
Okay. You want one?
Why are we looking
at Mormons and Jews?
Mormons tend to have
very large families,
which makes them
excellent genetic resources.
Plus the Church
of Latter Day Saints
believes everyone
related to the Mormons
has to be baptized
to be saved later.
So, what, there's carcinogens
in the baptismal water
they're using?
No. But they keep
incredibly detailed records
A researcher before us found
in one family.
Called the Kindred 107.
Ashkenazi Jews are
important, Tom, because
they have an extraordinarily
high rate of breast cancer.
In New York, it's an epidemic.
Okay. But...
why couldn't it be
the water or the air?
If that was true, it would be
true of all women in the area.
Breathing the same air,
drinking the same water.
- But it's not.
- So it's something in them.
In their genes.
You're early.
Dr. Gold's not here.
So how did you know
What stuff?
The medical stuff.
I used to be a nurse.
- You used to be a nurse?
- Yep.
- What happened?
- What do you mean, "what happened"?
You don't think
I enjoy this? Yes?
Okay.
Mr. Elson, you can
take your wife through
to the back with the nurse.
Seriously, what happened?
Uh...
I used to work
in the oncology ward.
But it was too much,
so I quit.
You're right. Cancer patients
are a pain in the ass.
- Sorry.
- Hello.
Yes, Doctor, the tests
will be ready this afternoon.
No, Doctor.
I would've told you.
Okay. Bye-bye.
- You're right.
- About what?
You're all a pain in the ass.
That's true.
- He likes you, you know.
- Who?
Dr. Gold?
Yeah, him.
- No.
- Yes, he does.
I'm married.
Of course.
What was I thinking?
Annie.
Hey. Hi.
Oh. Oh.
I could've gotten cancer
from my mom?
Like passed down?
Uh, there's no evidence
that you can get it passed down.
All cancer is
genetic in the end,
just not necessarily
in the beginning.
I don't understand.
When you get cancer,
and certain genes
can cause your cells
to replicate wildly.
But something
has to mess the DNA up
in the first place, right?
Right.
Well, then, what messes it up?
We don't know, really.
I really didn't mean
to upset you again.
It's not you. It's me.
It's the chemo, I think.
You know, I even cried
at the Leafs game
with Paul last night.
- You did?
- Yeah.
It was a tie,
but the players all looked so sad.
Hey, An...
Hey, hon.
Hon.
Annie...
Why?
Why? We've got doctors.
The chemo...
is going well...
you know?
I've gotta
do something. I...
Annie...
Hey, why can't you
just leave it alone?
I really didn't know.
I think that part
more than anything
drove him crazy.
Guys want reasons.
I should've made one up.
I don't know, Annie.
Maybe you need to give him time.
I've given him time.
Maybe it has something to do
with the...
- You know. The...
- What?
I don't know.
All the research.
It's a tiny, tiny bit obsessive.
Obsessive? How?
You know, like...
wacko obsessive.
Wacko obsessive.
It's not the bad kind, then.
It's not too late
to reach out to him
and to let him know
how you feel.
What, like a blow job?
Yeah, that's
exactly what I mean.
Have you guys heard
of Mary-Claire King?
She used dental genetics
to identify children
of parents murdered
by the junta in Argentina.
But she is also doing
some very interesting work
on the genetics
of breast cancer.
So I wrote to Dr. King,
and I wrote to her again,
and I wrote a third
and a fourth time.
I told her my story,
my family's story.
Books were hard for me,
so I could understand.
Cells, genes,
chromosomes, and a helix.
I'm going to the bar!
What?
because this is
I can't hear you!
I don't f***ing believe this.
I'm going out!
Hey, watch the rest of the game.
Remember the score.
Paul, would you
put William to bed?
We didn't discover much
in that first year,
but, oddly, that mattered
less and less.
Something mysterious
was taking hold of me.
I didn't know what it was then.
That would come later.
And then, some news.
Keep having you
in to do screenings
every six months or so
just as a precautionary measure,
but I would say that
cancer is out of your life.
You have reason to celebrate.
Done?
I'm done with chemo?
You're done with chemo.
Hey.
Hey. What is this?
Uh, Louise is watching William.
Okay. Um, I...
I wish you had told me.
- Why?
- 'Cause I have plans.
- You have plans?
- Yeah.
- What plans?
- Just...
You know, just plans.
I...
Can you just stay
and eat a little bit
before you go at least?
Yeah. Yeah.
Great.
Okay.
Can you change them?
- What?
- Your plans.
I kind of, uh...
I made this dinner
special for us, you know?
Thank you.
I know you went to...
a lot of trouble,
and it looks great.
- I just...
- No, no.
There's no trouble,
Paul, you know?
I'm married.
Married people do nice things
for each other.
I know.
They do things together...
like make love.
Annie, please, just...
We can have sex.
Don't do this.
Don't you love me anymore?
Annie, I do.
Hey, I want to.
You want to?
No, I... I do.
Well, then, I don't understand
what the problem is.
Why can't you make love
to me anymore?
Look, I just... I just...
I just can't.
- You can't?
- Okay? I can't.
Oh, is it because
I only have one breast?
- Is that what it is?
- Oh, my God, Annie.
Why don't you just, like,
only put it up halfway?
Maybe you could
get half-erect.
- Maybe you could close one eye.
- Annie, stop it!
- No, I will not stop it!
- Stop it! Stop!
I can't touch you!
Okay? I can't touch you!
Annie...
I can't even look at you,
at your body.
I mean, I hate that...
that hole, that scar.
I'm sorry. I just...
Paul...
Knudson's
two-hit theory?
Normal cells have
two undamaged chromosomes...
- ...one from the mom...
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